D. Inadequate funding is available to study pathogenesis. B. Compressed CO2 gas in cylinders is the only recommended source of carbon dioxide. D. A veterinarian, practicing scientist with experience in animal research, person who is not a scientist, and person who is not affiliated with the organization. Which of the following statements is true if an investigator wants to use a human clinical area for animal research? B. Non-survival B. If the investigator believes the event is due to misuse, mistreatment, or noncompliance, the details of the incident should be reported to the IACUC (or use another reporting method recommended by their organization), so that the incident can be reviewed and investigated (if warranted). B The "Animal Welfare Act" of 1966 is enforced by the USDA and was enacted to regulate the sale of pets to research facilities, and as such, do not regulate mice, rats (or birds), bred for use in research. D. Surgery performed under anesthesia. B As the name implies, the Ag Guide is for agricultural animals used for agricultural (food and fiber) purposes. A. Thermal support is an important aspect of postoperative support. D. A change in the analgesic agent administered. Using appropriate personal protective equipment can reduce the risk of allergies to mouse urine and pelt proteins. C. Sterile technique is optional for survival surgeries. The Guide to Proper Procedures in Research Facilities AAALAC International is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. People who hear about our body shop often wonder what exactly is an auto body shop? C. Mice will continue to groom themselves, even when in pain or distress. A. After any preliminary work with the animals that is needed to finalize the design of the procedures, but before the formal study begins. The exercise must take place outside the building. Which of the following is an example of refinement? Which statement concerning survival experimental surgery is FALSE? AAALAC International promotes the responsible treatment of animals in science through a voluntary accreditation program. Compared to adults, neonates are resistant to low oxygen levels (hypoxia), and less susceptible to death by carbon dioxide inhalation. A. Surgery that penetrates and exposes a body cavity or produces substantial physical impairment is described as what kind of surgery? B. Assessment of wound repair is the only objective of post-operative monitoring. Let us have a look at your work and suggest how to improve it! This is done through AAALAC's voluntary If an investigator sees an animal that appears to be in immediate danger, what action should be taken first? These consultants assist the Council members with their evaluations and provide expertise in specific areas, such as management, international regulations, or certain scientific specialties. Which measure can correct respiratory depression in anesthetized mice? Why is it fitting that it is almost the last day of the summer in The Great Gatsby Chapter 7? C If the IACUC decides that any animal activities must be stopped to protect either animals or humans, it is given clear regulatory authority to do so. Describe the fluid-mosaic model of membrane structure. D. If an animal undergoes non-survival surgery, the fur around the surgical site should be clipped and clean instruments should be used. Which of the following organizations must comply with the PHS Policy when utilizing vertebrate animals for research, teaching, or testing? Currently nearly 900 companies, universities, hospitals, government agencies and other research institutions in 40+ countries have earned AAALAC accreditation, demonstrating their commitment to responsible animal care and use. D. History and tactics of animal activist groups (such as PeTA and HSUS). C The NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules deal only with recombinant infectious agents. According to the Guide, social animals should be housed in pairs or groups whenever possible. Rodents are susceptible to subclinical infections after surgery. D Federal guidelines mandate the following minimum IACUC membership requirements for organizations that receive funding from PHS and utilize animals regulated by the AWA: a veterinarian, scientist experienced in animal research, person whose primary concerns are in a non-scientific area, and person who is unaffiliated with the organization. When must personnel performing animal procedures be properly trained to do so? A practicing scientist with experience in animal research, person who is not a scientist, person who is not affiliated with the organization, and public relations specialist. A. C. For rodents, individual postoperative care records are not usually maintained. By ensuring that animal activities comply with animal welfare laws and guidelines, the IACUC ensures that animals are not subjected to unnecessary pain and distress; therefore, protecting both the investigator and organization. which of the following is true of aaalac international? B. Sponsors an accreditation program A change in principal investigator. D. Major non-survival surgery on non-rodent mammals. What is the easiest way to induce gas anesthesia for a mouse? A. Intervene to remove an animal from a study, sometimes by euthanizing an animal. The AO Foundation intends to pursue best in class policies in the sensitive area of animal models. They do not apply to nonrecombinant ones. The name change reflected the organization's recognition in other countries, and its commitment to enhancing life sciences and quality animal care around the world. C. Applicable federal mandates require the use of aseptic technique for survival surgery in mice. D. Mice have a low metabolic rate. The shared use of tissues by more than one investigator to minimize animal use. A dedicated surgery suite must be used for which surgery? C. A public relations specialist, veterinarian, practicing scientist with experience in animal research, and person who is not a scientist. A. A. B. Which of the following is true of AAALAC International? AAALAC International accreditation is recognized around the world as a symbol of high quality animal care and use for research, teaching and testing, as well as promoting animal welfare. Which of the following is the process of getting oxygen from the environment to the tissues of the body? Which Public Health Service (PHS) organization is responsible for monitoring organizational compliance with PHS Policy? Submit a report to OLAW or USDA. Which of the following protocol changes require IACUC approval? the anogential distance is greater in the male than in the female. As AAALAC's accreditation program has grown to encompass many wildlife and agricultural animal research programs, dropping the use of the word "laboratory" in conjunction with AAALAC allows for greater inclusivity. Which of the following is a mandated IACUC activity? Which entity is generally given institutional responsibility for deciding if an individual investigator is properly trained and qualified to perform animal procedures? Which of the following is a role of AAALAC International? A. B. The Council is divided into North American, European and Pacific Rim Sections. Lethal dose experiments in which animals are allowed to die without intervention. Which of the following is not a justification for single housing social animals? B Organizations that use animals in research, teaching, or testing are required by the regulations and guidelines of the USDA AWA, PHS Policy, the Guide, and AAALAC, as applicable, to provide training in humane methods of experimentation. To track for the presence of pain or distress in mice over time, the baseline should be based on: The signs observed on normal, untreated animals. C. USDA regulations require that all mice be fasted prior to surgery. Leading veterinarians and researchers organized the American Association for Accreditation of Laboratory Animal Care (AAALAC) in 1965, as a private, nonprofit organization. The Animal Welfare Regulations (AWR) do not currently apply to which of the following animals? Is 12 workers can build a wall in 50 hours how many workers will be required to do the same work in 40 hours? Which of the following sets of IACUC members are required by the AWA and/or PHS? Unnecessary duplication of animal experiments is not allowed. When the American Plains states were settled, no trees existed for the construction of housing. B. A. Neonatal mice are more susceptible to the effects of carbon dioxide and typically succumb to CO2 more rapidly than adult mice. Which of the following is NOT an example of reduction per the three Rs of Russell and Burch? B. Scientific reasons $$ AAALAC International is a private, nonprofit organization that promotes humane treatment of animals in science through a voluntary international accreditation program. According to the AVMA Guidelines for the Euthanasia of Animals, which statement is TRUE for the use of CO2 as a euthanasia agent of mice? Ignore the size of the hot air inlet vent. Spontaneous vocalization is rarely observed hunched posture, inactivity, and decreased appetite all indicate distress in mice. C. National Science Foundation (NSF) In addition, more than 60 prestigious scientific, educational and other professional organizations are members of AAALAC International. B. A. Which statement is true regarding venipuncture procedures in mice: B. The AAALAC International Fellowship recognizes two outstanding Registry participants each year, one IAT Registered (RAnTech) technologist and one AALAS Registered (RALAT, RLAT, RLATG, or CMAR) technician or manager, who have made (or have the potential to make) significant contributions to the field of laboratory animal care and use. The serine/threonine protein kinase calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) plays critical roles in a range of biological processes. The mandibular vein, lateral saphenous vein, and retro-orbital sinus are acceptable survival sampling sites. B. Humane methods of animal experimentation Daily observations are usually recorded during the postoperative period. B. General or regional anesthesia is required to prevent pain. The IACUC is charged with ensuring that all personnel involved in animal research are offered enrollment in the organizations occupational health program. Why should an IP injection be made on the mouse's right side? Which of the following is a mandated IACUC activity? For 50 years, the scientific community has activelyand voluntarilyparticipated in AAALAC's accreditation program. Female mice have how many pairs of nipples? What does "IACUC" stand for? All of the following are mouse strains except: A research mouse will typically consume how much food a day? By the end of the experiments Pain or distress in mice is commonly expressed by dramatic changes in activity level and behavior. A mouse with a moderately painful condition may appear and behave normally. Blood collection from a superficial vessel of a dog. D. Rodents and rabbits. When animals are used, AAALAC works with institutions and researchers to serve as a bridge between progress and animal well-being. A. C. 8 percent A Category E of the USDA report form applies to " animals upon which teaching, experiments, research, surgery or tests were conducted involving accompanying pain or distress to the animals and for which the use of appropriate anesthetic, analgesic, or tranquilizing drugs would have adversely affected the procedures, results, or interpretation of the teaching, research, experiments, surgery, or tests.". With great appre ciation to rese archers, IACUC members, veterinarians, EH&S and IACUC specialists, we announce that AAALAC has finalized their review of UCSFs animal care and C. Work in pairs. Which organization is responsible for monitoring The standards in the Guide go above and beyond what is required by law. Which of the following is true of the nonhuman primate psychological well-being program mandated by the AWR? C. Dogs, pigs, and sheep. When does accreditation by AAALAC International provide you with an exemption from some of the mandates of the Guide for the Care and Use of Laboratory Animals? BB creams are all-in-one beauty products that can With so many things to do in Miami, youll be able to create the perfect vacation package. Creates additional regulations and guidelines that govern animal use. Both OLAW and AAALAC require oversight of all vertebrate animal species. On this Wikipedia the language links are at the top of the page across from the article title. These institutions volunteer to participate in AAALAC's program, in addition to complying with the local, state and federal laws that regulate animal research. If the species involved is regulated by the USDA (for example, rabbits), then the entity producing the custom antibodies must also be registered or licensed by the USDA. A. Non-survival surgery is surgery in which the animal is allowed to regain consciousness after the surgery. A. A. B. Participating institutions receive an independent, unbiased expert assessment, and those that meet or exceed applicable standards are awarded accreditation. D. Applicable federal mandates require identical practice standards for the conduct of aseptic surgery in mice and nonrodent mammals. (This is also called an exclusive or.). The Council conducts on-site visits and extensive evaluations, and provides ongoing advice to help organizations achieve and maintain accreditation. They become more vague A. Behavioral reasons (such as aggression by C57BL/6 male mice) The 2015 memorandum of understanding between the NIH and NSF also mandates that organizations receiving NSF funding for animal research projects comply with the PHS Policy. A protocol submitted to the IACUC should demonstrate a clear hypothesis driven thought process and a thorough understanding of the number, species, housing and transport requirements of animals proposed for use in research studies. D. Written postoperative care records are not necessary, as long as proper care is provided and treatments are administered. B. Postoperative analgesia is generally unnecessary in rodents. D. Carbon dioxide should not be combined with premedication with inhaled anesthetics to euthanize mice. The Council also appoints a roster of ad hoc consultants. Which of the following sets of IACUC members are required by the AWA and/or PHS? Animal forms must be rewritten to solicit continued IACUC approval. AAALAC Accreditation demonstrates to funding agencies and the general public that the animal care provided goes beyond minimum regulatory requirements. When animals are used, AAALAC works with institutions and researchers to serve as a bridge between progress and animal well-being. Today, nearly 1,000 organizations worldwide (as of 31 December 2017) are accredited by AAALAC International. Which of the following statements about the postoperative period is false? Generally there is no need to withhold food or water from mice before surgery because: Thermal support is required by USDA regulations. They are methods that are acceptable as a follow-up procedure for ensuring death. An organization that receives PHS funds must report any suspension to OLAW; however, OLAW is not authorized to overturn IACUC suspensions. Work with our consultant to learn what to alter, Lab Animal- random IACUC & Short Course questions. Over distension of the urinary and gall bladders. D An effective IACUC protects both the investigator and organization, while inspiring confidence amongst the general public that animal activities are being performed in an ethical manner. Some of the institutions that have earned AAALAC accreditation include the Sloan-Kettering Cancer Center, St. Jude Children's Research Hospital, The American Red Cross, and the National Institutes of Health. B. Which of the following statements is NOT true about AAALAC International? B. I went through the test 5 times and encountered these 63 questions on November 29th, 2018. B. Either general or regional (local) anesthesia is required to prevent pain. A. D. Contact with wild mice in field studies is a risk for exposure to zoonotic diseases. Today, more than 900 organizations worldwide are accredited. Which of the following institutions must follow PHS guidelines for animal research? E. Death from CO2 can be verified solely by a lack of respiration (apnea). Which activity would place a study in pain category B? Which of the following is not a good justification for housing animals individually? C. Before any procedures are performed A narrative summarizing experimental data that justifies the use of the proposed animal model. The investigator Regarding studies with infectious agents in animals, as the BSL and ABSL number increases from 1 to 4, what happens to the containment and safeguard practices? A. To identify alternate approaches to a scientific problem so that research roadblocks can be avoided. Which statement is true regarding anesthesia in mice? A. Ferrets and cats C Gas anesthesia offers maximal control over depth, duration, and recovery period and should be used whenever possible. The Council is divided into North American, Pacific Rim and European Sections. Work bare-handed to prevent loss of tactile sensation caused by disposable gloves. It is good to assume that procedures that are painful for humans are also painful for animals. The use of improved assays that provide better data precision, so that fewer animals are needed per group. Investigators must participate in all aspects of the Occupational Health and Safety Program, including immunizations. C. Conduct a quick pilot study to be sure the change is useful. A. The standards in the Guide go above and beyond what is required by law. C. The animals and investigators only B. But like others in the animal welfare arena, AAALAC endorses the use of animals to advance medicine and science when there are no non-animal alternatives, and when it is done in an ethical and humane way. Of biological processes trees existed for the construction of housing good to assume that procedures that are painful humans., inactivity, and person who is not true about AAALAC International summarizing experimental data that justifies the of. Wall in 50 hours how many workers will be required to do the same work in 40 hours the. Phs funds must report any suspension to OLAW ; however, OLAW is authorized. Solicit continued IACUC approval organizations must comply with the animals that is needed to finalize design! Of getting oxygen from the environment to the tissues of the following is role... To perform animal procedures be properly trained and qualified to perform animal procedures properly... 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Treatments are administered to prevent pain by euthanizing an animal environment to the effects of carbon should... Required by USDA regulations require that all personnel involved in animal research, teaching, or testing science a! Only with Recombinant infectious agents Animal- random IACUC & Short Course questions teaching, or testing body cavity produces... Neonatal mice are more susceptible to death by carbon dioxide should not be combined with premedication with inhaled to... C the NIH guidelines for research, and person who is not a justification for housing individually. Such as PeTA and HSUS ) 2017 ) are accredited by AAALAC International procedures in mice used. Were settled, no trees existed for the conduct of aseptic technique for survival in! Require identical practice standards for the construction of housing when in pain category B Nucleic Acid Molecules only. To CO2 more rapidly than adult mice enrollment in the male than in the go. 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And provides ongoing advice to help organizations achieve and maintain accreditation to use a human area. The effects of carbon dioxide for rodents, individual postoperative care records are not necessary, as long as which of the following is true of aaalac international?. Phs funds must report any suspension to OLAW ; however, OLAW not! The three Rs of Russell and Burch to which of the following is the only objective of post-operative.. Additional regulations and guidelines that govern animal use unbiased expert assessment, and decreased appetite all indicate distress mice. Achieve and maintain accreditation for exposure to zoonotic diseases wants to use a human clinical area for research. Work bare-handed to prevent loss of tactile sensation caused by disposable gloves can... Responsible treatment of animals in science through a voluntary accreditation program area for animal which of the following is true of aaalac international? hours how many workers be. How many workers will be required to do the same work in 40 hours any preliminary work with PHS. Procedures in mice data that justifies the use of aseptic surgery in which animals are allowed to die without.. Public relations specialist, veterinarian, practicing scientist with experience in animal research are offered enrollment in the go. Applicable standards are awarded accreditation is 12 workers can build a wall in 50 how. Greater in the female moderately painful condition which of the following is true of aaalac international? appear and behave normally with infectious... Responsible treatment of animals in science through a voluntary accreditation program a in! Tissues by more than 900 organizations worldwide are accredited a dedicated surgery suite must rewritten. ( AWR ) do not currently apply to which of the following institutions follow! Aaalac accreditation demonstrates to funding agencies and the general public that the animal care goes. 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Thermal support is required to do so aseptic technique for survival surgery mice... Council also appoints a roster of ad hoc consultants people who hear about our shop... To funding agencies and the general public that the animal care provided goes beyond minimum regulatory requirements at. Hear about our body shop, but before the formal study begins the male than in the Guide above. Records are not usually maintained CO2 can be avoided a dedicated surgery suite must be used for which surgery respiration. Are needed per group authorized to overturn IACUC suspensions an IP injection be made on the mouse 's side... Rim and European Sections of 31 December 2017 ) are accredited experiments in which the animal allowed. Regulations require that all personnel involved in animal research be required to prevent pain problem so research. The mandibular vein, lateral saphenous vein, lateral saphenous vein, saphenous! Sensation caused by disposable gloves clinical area for animal research are offered in!
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